OxyContin

Generic Name: oxycodone (ox i KOE done)
Brand Names: M-Oxy, OxyContin, Oxyir, Percolone, Roxicodone

What is OxyContin?

OxyContin is in a class of drugs called narcotic analgesics. OxyContin is a pain reliever.

OxyContin is used to treat moderate-to-severe pain.

OxyContin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about OxyContin?

Do not crush, chew, or break controlled-release forms of oxycodone such as Oxycontin. Swallow them whole. They are specially formulated to release oxycodone slowly into your system. Breaking the OxyContin tablet would cause too much drug to be released into the blood at one time leading to a potentially fatal dose of oxycodone. Use caution when driving, operating machinery, or performing other hazardous activities. OxyContin will cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities. Avoid alcohol while taking OxyContin. Alcohol will greatly increase the drowsiness and dizziness caused by OxyContin and could be dangerous.

OxyContin may increase the effects of other drugs that cause drowsiness, including antidepressants, other antihistamines, other pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if OxyContin is taken with any of these medications.

Never take more OxyContin than is prescribed for you. Taking too much OxyContin could result in serious side effects, even death. If your pain is not being adequately treated, talk to your doctor.

Do not share this medication with anyone else.

Who should not take OxyContin?

OxyContin is habit forming and should only be used under close supervision by patients with an alcohol or drug addiction.

Before taking this medication, tell your doctor if you have

• kidney disease;
• liver disease;

• asthma;

• urinary retention;

• an enlarged prostate;

• hypothyroidism;

• seizures or epilepsy;

• gallbladder disease;

• a head injury; or

• Addison's disease.

You may not be able to take OxyContin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

OxyContin is in the FDA pregnancy category B. This means that it is unlikely to cause birth defects. However, OxyContin may cause addiction and withdrawal symptoms, difficulty breathing, as well as other harmful effects in a newborn baby when taken during pregnancy. Do not take OxyContin without first talking to your doctor if you are pregnant. OxyContin may cause addiction and withdrawal symptoms, difficulty breathing, and sedation in a nursing infant. Do not take OxyContin without first talking to your doctor if you are breast-feeding a baby.

How should I take OxyContin?

Take OxyContin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. OxyContin can be taken with food or milk if stomach upset occurs.

Never take more OxyContin than is prescribed for you. Taking too much OxyContin could result in serious side effects, even death. If your pain is not being adequately treated, talk to your doctor.

Do not crush, chew, or break controlled-release forms of oxycodone such as Oxycontin. Swallow them whole. They are specially formulated to release oxycodone slowly into your system. Breaking them would cause too much drug to be released into the blood at one time leading to a potentially fatal dose of oxycodone.

Occasionally, empty Oxycontin tablets may be passed out in the stool. This is not a problem. The active medication has been absorbed in the body and the empty tablet shell may appear in the stool.

Do not stop taking OxyContin suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you uncomfortable. Your doctor may want to gradually reduce the dose. Increasing the amount of fiber and water (six to eight full glasses) in your diet may alleviate constipation. Do not share this medication with anyone else. Store OxyContin at room temperature away from moisture and heat and out of the reach of children. When treatment with OxyContin is no longer needed, any remaining medication should be destroyed by flushing down the toilet.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking the next dose.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of an OxyContin overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, and small pupils.

What should I avoid while taking OxyContin?

Avoid alcohol while taking OxyContin. Alcohol will greatly increase the drowsiness and dizziness caused by OxyContin and could be dangerous.

OxyContin may increase the effects of other drugs that cause drowsiness, including antidepressants, other antihistamines, other pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if OxyContin is taken with any of these medications.

Use caution when driving, operating machinery, or performing other hazardous activities. OxyContin will cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.

What are the possible side effects of OxyContin?

If you experience any of the following serious side effects, stop taking OxyContin and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• slow, weak breathing;

• seizures;

• cold, clammy skin;

• severe weakness or dizziness; or

• unconsciousness.

Other, less serious side effects may be more likely to occur. Continue to take OxyContin and talk to your doctor if you experience

• constipation;

• dry mouth, nausea, vomiting, or decreased appetite;

• dizziness, tiredness, or lightheadedness;

• muscle twitches;

• sweating;

• itching;

• decreased urination; or

• decreased sex drive.

Do not stop taking OxyContin suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you uncomfortable. Your doctor may want to gradually reduce the dose.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect OxyContin?

OxyContin may increase the effects of other drugs that cause drowsiness, including antidepressants, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if OxyContin is taken with any of these medications.

Drugs other than those listed here may also interact with OxyContin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about OxyContin written for health professionals that you may read.

What does my medication look like?

Oxycodone is available with a prescription generically and under several brand names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Roxicodone 5 mg - white, scored tablets

• Roxicodone Solution 5 mg per 5 mL (1 tsp)

• Roxicodone Concentrated Solution 20 mg per 1 mL

• OxyIR 5 mg - beige/orange capsules

• Oxycontin 10 mg - round, white, convex, unscored tablets

• Oxycontin 20 mg - round, pink, convex, unscored tablets

• Oxycontin 40 gm - round, yellow, convex, unscored tablets

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.